- Dietary Supplement
- Hypoallergenic
- To Support Estrogen Metabolism
- Maintains Optimal 2-Hydroxy/16-Hydroxy Estrogen Ratios
- Found in Cabbage Family Vegetables, it's a Source of DIM
- Nutritional Support for Liver Detoxification
- Made Without Flowing Agents that can Inhibit Bioavailability
Indole-3-carbinol (I3C) is a mixture present in high concentrations in the Brassica family vegetables, involving broccoli, cauliflower, Brussels sprouts, and cabbage.
As a dietary supplement, I3C offers vital nutrimental support for the detoxification of liver. It also plays a significant role in assiting the reproductive health of the female. The most of I3C ingested is assimilated in the small intestine as diindolylmethane (DIM), which is identified to be the initial contributor to the beneficial properties of I3C. DIM has been demonstrated to selectively tied to the receptors of estogen and may function as an estrogen antagonist at physiological concentration.
In the liver, I3C improves the estrogen metabolism and raises the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen. The 2-hydroxy estrogens, is less active than the 16-hydroxy estrogens, usually are removed more swiftly from the body. One prospective research found postmenopausal women with the most beneficial urinary 2:16-hydroxyestrone ratio were most presumably to keep good female health.
Primary studies have analysed the potency, safety, and I3C supplementation in optimum . An I trial a pahse around 12 week conducted on 17 women seen a 66-percent increase in the urinary 2:16-hydroxyestrone ratio with 400 mg I3C daily administration.
